Comparative Assessment of Serum Lipid Profile and Uric Acid between Pregnant Normotensive and Hypertensive Women in Port Harcourt
Published: 2022-12-30
Page: 348- 353
Issue: 2022 - Volume 5 [Issue 1]
Tamuno-Opubo, Abiye *
Department of Human Physiology, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
Stanley, Rosemary Oluchi
Department of Internal Medicine, University of Port Harcourt Teaching Hospital, Rivers State, Nigeria.
Bademosi Adetomi
Department of Community Medicine, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
Austin-Asomeji, Iyingiala
Department of Community Medicine, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
George Abiye
Department of Anaesthesiology, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
Obiandu Chibuike
Department of Human Physiology, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
Orabere, Josephine Tamunomiebaka
Department of Human Physiology, College of Medical Sciences, Rivers State University, Rivers State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Aim: The aim of this study was to compare the serum lipid profile and uric acid between normotensive and hypertensive pregnant women.
Study Design: Comparative Cohort study.
Study Area and Duration: Port Harcourt, Nigeria. January – July, 2022.
Methods: A cross-sectional study was carried out among 50 hypertensive and 50 normotensive pregnant women from RSUTH, PH. Blood pressure was measured. Demographic data such as age, parity gestational age was collected. Fasting blood samples were collected and analyzed for total cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL) and uric acid.
Results: The study showed a significantly higher (P< 0.05) level of TC and LDL among the hypertensive group compared to the normotensive group. There was no statistically significant difference in the uric acid levels between the subcategories of the study group.
Conclusion: From the results of the present study, it was concluded that PIH is associated with increased levels of TC and LDL. This association may be important in understanding the pathologic processes of the disease and in developing strategies for its prevention and early diagnosis.
Keywords: Pregnancy, normotensive, hypertensive, lipid profile, uric acid